TDI Urine Testing

TDI urine testing measures urinary toluene diamine (TDA) isomers as the biomarker for toluene diisocyanate exposure in flexible foam, surface coating and elastomer manufacture.

Biomarker and method

Both 2,4-TDA and 2,6-TDA are measured following acid hydrolysis; the sum is reported per mol creatinine. The HSE BMGV is 1 µmol/mol creatinine for the sum.

Sectors monitored

Flexible PU foam production, TDI-based coatings, and certain elastomer and adhesive operations. TDI is more volatile than MDI and demands particular attention to LEV at mixing and pour stations.

Isocyanate Biological Monitoring
Isocyanate Urine Testing
MDI Urine Testing
Spray Painting Biological Monitoring